PPH77020 - Neuroscientific Basis of Psychopharmacology II: Neurochemistry, Neuropathology

(3 units)

This course covers major neurotransmitter systems: acetylcholine, dopamine, norepinephrine, serotonin, amino acid neurotransmitters and opioid neuropeptides. Topics for each include: anatomical distribution, synthesis, inactivation, synaptic specializations, pharmacology of specific receptor subtypes, second messenger systems and associated behavioral roles. Pathophysiology associated with different neurotransmitter pathways will be discussed. Additional topics include the anatomy and manifestation of dementia, delirium, and other cognitive disorders; movement, vascular, and seizure disorders; traumatic brain injury; other pathologies of the nervous system, and extrapyramidal dysfunction.